What is a haptoglobin Test? Why is the test done? Everything around this, that you should know, in this post, and of course our doctors are always there to help you. Just fill in your details in the form below and we will answer all your questions for FREE!
Haptoglobin is a colourless protein which is produced by the liver and circulates in the body. Generally, it is produced by hepatocytes but also by other tissues e.g. skin, lungs, and kidney.
Haptoglobin is an acute-phase protein capable of binding haemoglobin, and it helps prevent iron loss and renal damage. It shows its function as an antioxidant, has antibacterial activity, and manages many aspects of acute phase response.
The haptoglobin test measures the amount of haptoglobin in the blood.
Haptoglobin binds with haemoglobin, which is a protein that is found in red blood cells. When red blood cells are destroyed, they release more haemoglobin in the bloodstream and it is called “free haemoglobin.’’ It attaches to the free haemoglobin to create the haptoglobin-haemoglobin complex. This complex goes to the liver, where it is removed from the body.
This test is most often used to diagnose hemolytic anaemia. Hemolytic anaemia is a blood disorder that happens when red blood cells are destroyed faster than they can be replaced. This test may also be used to see if another blood disorder or another type of anaemia is causing the symptoms.
This test may be performed when having symptoms of anaemia. These may include:
This test also may be used if someone had a blood transfusion. A haptoglobin test may be done along with another test called direct anti-globulin.
The increased level of haptoglobin is seen in the following conditions:
Disease-associated with increased ESR (erythrocyte sediment rate) such as infection, inflammation, trauma, hepatitis, amyloidosis, lymphoma, collagen disease, and leukaemia.
If the results show that haptoglobin levels are lower than normal. The following conditions may include:
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** The text on this website is sourced from websites like emedicine and/or other verified material by government agencies around the globe along with valuable inputs and additions by our team. The content of this page is proofread and updated by the team of doctors, every once in a while, to provide the most accurate information.
