Follicular Thyroid Carcinoma

Follicular thyroid cancer accounts for 15% of thyroid cancer. Follicular thyroid carcinoma (FTC) is a well-differentiated tumor.

follicular thyroid carcinoma

 

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Race which are prone to Follicular Thyroid Carcinoma

FTC occurs more frequently in whites than in blacks

Age / Sex prevalence of Follicular Thyroid Carcinoma

Incidence is higher in women than men.Thyroid carcinoma is common in all age groups, with an age range of 15-84 years

Causes of Follicular Thyroid Carcinoma

Exposure to ionizing radiation
• Iodine deficiency
• Mutations of the ras oncogene

Signs and Symptoms Follicular Thyroid Carcinoma

Thyroid mass or nodule in neck.
• Persistent cough
• Difficulty breathing
• Difficulty swallowing
• Pain
• Stridor
• Vocal cord paralysis
• Hemoptysis

Investigations of Follicular Thyroid Carcinoma

Complete assessment of thyroid function: Levels above the reference range of T4, T3 and TSH may indicate thyroid cancer.
• Evaluate serum levels of thyroglobulin, calcium, and calcitonin.
• TSH suppression test
• PCR Technique
• USG
• Fine needle aspiration biopsy
• Fiber-optic laryngoscopy

Treatment for Follicular Thyroid Carcinoma

The initial treatment for cancer of the thyroid is surgical.
• Thyroid replacement therapy
• External beam radiation therapy
• Chemotherapy with cisplatin or doxorubicin has limited efficacy

Prognosis of Follicular Thyroid Carcinoma

The overall 5-year survival rate for follicular thyroid cancer is 91% and 10 years survival rate is 85%

Differential diagnosis of Follicular Thyroid Carcinoma

• Goiter
• Goiter, Toxic Nodular
• Graves Disease
• Hurthle Cell Carcinoma
• Thyroid Nodule
• Papillary Thyroid Carcinoma
• Medullary thyroid carcinoma
• Anaplastic thyroid carcinoma

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