What is Coomb’s Test? What does it indicate? How is it done? What is direct and indirect coombs test? Everything around this, that you should know, in this post and of course our doctors always there to help you. Just fill in your details in the form down below and we will answer all your questions for FREE!
What is coomb’s test?
This test is used to detect presence of antibody against RBC or to evaluate destruction of RBC.
It is of two type:
Indirect and direct coomb’s test
Indirect coomb’s test means it measures the liquid part of blood (plasma).It is also known as indirect antiglobulin test(IAT).
Direct coomb’s test means it measures the red blood cell present in the blood.It is also known as direct antiglobulin test(DAT).
Why do I need this test?
This test is needed to detect following conditions:
Autoimmune hemolytic anemia
Cold autoimmune hemolytic anemia
Hemolytic disease of fetus
HUS – Hemolytic uremic syndrome
Paroxysmal cold hemoglobinuria
Transfusion reaction due to blood group antibody-antigen mismatch
Why is coombs test done?
Coomb’s test is used to determine the cause of hemolytic anemia(it is a condition in which red blood cells (RBCs) are destroyed which is due to antibodies attached to red blood cell( RBCs)
What does a positive coomb’s test mean?
Coombs test positive means person have antibodies that act against red blood cells. It may be due to: Autoimmune hemolytic anemia, Chronic lymphocytic leukemia. Blood disease of newborns called erythroblastosis fetalis (also called hemolytic disease of the newborn)in that case baby need a transfusion with compatible blood to prevent anemia.
What happen if test is negative?
Coomb’s test negative means fetus is not in danger of problems relating to Rh incompatibility.
Any preparation for this test?
No preparation is needed
How it is measured?
Measurement is made using a blood sample from a vein. The sample is then taken to a laboratory and analyzed.
For more information, you can visit Wikipedia and Stanford Medicine.
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