Zollinger Ellison Syndrome

Homeopathic_doctor_chandigarh_zollinger_1 Zollinger-Ellison syndrome is a condition in which there is increased production of the hormone gastrin.

Zollinger-Ellison syndrome  is caused by tumors producing hormone gastrin called as gastrinomas , usually found in the head of the pancreas and the upper small intestine. High level of gastrin causes increased acid production in stomach causing inflammation and ulcers in stomach and food pipe .

Gastrinomas mainly affect people of age group between 30-50 years of age and men are more affected than women .
Gastrinomas occur as single tumors or as small, multiple tumors.

Races affected by Zollinger Ellison Syndrome

Zollinger Ellison syndrome affects people of all races.

Age/Sex prevalence of Zollinger Ellison Syndrome

Zollinger usually affects people of age group between 30 and 50 years .

Causes of Zollinger Ellison Syndrome

• Tumors, usually found in the head of the pancreas and the upper small intestine. These tumors produce the hormone gastrin and are called gastrinomas.

• High levels of gastrin cause production of too much stomach acid.

• Gastrinomas occur as single tumors or as small, multiple tumors. About one-half to two-thirds of single gastrinomas are cancerous (malignant) tumors that often spread to the liver and nearby lymph nodes.

Zollinger Ellison Syndrome Signs and Symptoms

• Abdominal pain is the most common symptom, present in majority of patients.
• 73% of patients with Zollinger  have diarrhea
• The combination of diarrhea and abdominal pain is present in more than half the patients.
• Heartburn is the third most common symptom
• Nausea, vomiting, gastrointestinal bleeding, and weight loss, weakness
Sometimes it is accompanied with digestive tract bleeding .

Investigations of Zollinger Ellison Syndrome

• Abdomonal CT scan
• Endoscopic ultrasound
• Secretin stimulation test
• Fasting serum gastrin

Complications of Zollinger Ellison Syndrome

• Failure to locate the tumor during surgery
• Intestinal bleeding or hole (perforation) from ulcers in the stomach
• Severe diarrhea and weight loss
• Spread of the tumor to other organs (most often liver and lymph nodes)

Treatment of Zollinger Ellison Syndrome

• If the patient is acutely ill, immediate control of gastric acid hypersecretion can be achieved with intravenous proton pump inhibitors. Previously, this was accomplished with histamine 2 (H2) receptor blockers. Intravenous pantoprazole was approved recently by the US Food and Drug Administration. Proton pump inhibitors are superior to H2 blockers for the control of gastric acid hypersecretion.

• Patients who are candidates for surgical resection should be referred for resection of the tumor.

• For patients with metastatic disease, chemotherapy, interferon, and octreotide may be helpful. The response to these agents in most studies has been low. Liver transplantation for hepatic metastasis also has been reported. For patients with a single confined liver metastatic lesion, surgical resection may be attempted.

Prognosis of zollinger ellison syndrome

Prognosis is very good in patients without any metastatic disease.

Homeopathic treatment for Zollinger Ellison Syndrome

Every branch of science has its own scope and limitations, so does Homeopathy. Although Homeopathy has a lot of very good remedies for curing auto-immune disorders, male & female disorders, children and elderly people.

In cases of any emergency situation such as poisoning, serious abdominal complaints, fractures, injury, and accidents should be treated first surgically .However a patient can consult his homeopathic physician for recovering from his after pains. Please note Homeopathy plays no role in treating any nutritional disorders.

The scope of Homeopathy is limited; it is the sole responsibility of the physician to decide upon the cure – by looking into the complete nature of the disease, onset and stage of the disease and then act accordingly.

Nux vomica –
• Soreness of abdominal walls
• Sour taste and nausea in morning
• Stomach region sensitive to stomach
• Weakness in region of abdominal ring

Nitric acid
• Gastric ulcers
• Longing for fat and salt
• Dyspepsia with excess of uric acid and phosphates

Hydrastis canadensis –
• Sore feeling in stomach
• Weak digestion
• Bitter taste ,cannot eat bread and vegetables
• Ulceration and cancer

Phosphoricum acidum –
• Nausea,symptoms following sour food and drink
• Craves juicy things
• Thirst for cold milk
• Aching in umblical region

Diet / management of Zollinger Ellison Syndrome

• Avoiding smoking and drinking alchol
• Drinking plenty of fluids
• Having small and frequent meals
• avoid caffeine

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