Lichen amyloidosis is a cutaneous condition characterized by the appearance of occasionally itchy lichenoid papules, appearing on the shins bilaterally.
The disease occurs most frequently in persons aged 50-60 years. It is more common in males than in females.
It is believed to be more common in persons of Chinese ancestry
Amyloid deposits in lichen amyloidosis bind to antikeratin antibodies.These deposits contain sulfhydryl groups, pointing to altered keratin as a source for these deposits.
Presents as intensely pruritic, red brown hyperkeratotic papules most commonly seen in pretibial surfaces i.e on shins.
A skin biopsy may be performed in lichen amyloidosis.
• Sedative antihistamines
• Topical and intralesional steroids
• Topical dimethyl sulfaoxide , a chemical solvent
• Surgical care :Include laser vaporization, dermabrasion and excision of individual lesion.Any of these can be the choice of treatment.
• Prurigo nodularis
• Lichen sclerosus et Atrophicus
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