Guillain Barre syndrome also named as Landry-Guillain-Barre syndrome, acute idiopathic polyneuritis, acute inflammatory polyneuropathy, and acute inflammatory demyelinating polyneuropathy.
Guillain Barre syndrome as the name tells is defined as the acute inflammation of the peripheral nerves leading to weakness of the muscles and diminished reflexes and this inflammation occurs when body’s immune cells attack the healthy neuron cells of the body and damage them.
Severe cases of the inflammation in guillian barre syndrome can lead to paralysis and even life-threatening conditionWho Are At Risk?
Individuals of all age groups can be affected but the people who are young adults and older adults are at higher risk of getting infected.
Male to female ratio to be affected by guillian barre syndrome is 1.5:1.
Infants are at lower risk of developing Guillain barre syndrome.
The exact cause of Guillain-Barre syndrome is not known.
• It is an autoimmune disorder, a condition in which the body’s immune system begins to attack the body itself.
• Infection with the bacterium Campylobacter jejuni is one of the most common risk factors for GBS. Other Infections that may trigger GBS include: Mycoplasma ( pneumonia), CMV ( cytomegalovirus), Varicella – zoster virus.
Other predisposing factors include:
• Hodgkin’s lymphoma
• Weakness or tingling sensations in legs that spread to the upper body
• Unsteady gait or inability to walk
• A difficulty with eye movement, facial movement, speaking, chewing or swallowing
• Severe lower back pain
• Urinary incontinence
• Fast heart rate
• Low or high blood pressure
• Difficulty breathing
Major diagnosis is made by arms and legs getting weaker, loss of reflexes.
• Lumbar puncture -where reveals a high protein content in the cerebrospinal fluid.
• Nerve conduction studies -which demonstrate slowing of nerve conduction in the nerve roots and/or peripheral nerves.
• Electromyography -EMG detecting the electrical activity in muscles
• Cerebrospinal fluid analysis
• Intravenous immunoglobulin
• plasma exchange (plasmapheresis)
Recovery usually begins in two to three weeks and may be accompanied by pain and tingling in the limbs.
• Breathing difficulties.
• Cardiovascular problems. Blood pressure fluctuations and cardiac arrhythmias
• Neuropathic pain
• Bowel and bladder function problems.
• Blood clots.
• This medicine acts very well on the nervous system.
• Debilty is the marked feature.
• There are paralytic weakness and spasm paralysis.
• There is the paralytic weakness in limbs due to which patient drops things.
• There is dizziness and weakness when descending.
• There is spasmodic twitching in muscles of forearm and hand.
• Fingers jerk when holding a pen.
• Well indicated for neuritis.
• Well indicated for typewriter’s paralysis.
• Well indicated medicine for lead paralysis is chiefly of extensor, forearm or upper limb, from center to periphery with partial anesthesia or hyperesthesia which is preceded by pain.
• There is localized neuralgic pain, neuritis.
• There is a constrictive sensation in internal organs.
• Indicated for infantile paralysis and bulbar paralysis.
• Acts well on neuroaxis and the anterior horns.
• There are lightening like pains in the back.
• There is paralysis of single muscles.
• Ptient is unable to lift or raise anything with hands.
• Well indicated medicine for neuritis with tingling, burning, and numbness.
• Great remedy for injuries to nerves.
• Patient complains of neuralgia and neuritis.
• There is pressure along the ulnar side of the arm.
• There is a pain in toes and fingers, especially in the tips.
• This medicine is well indicated for most horrible neuralgic, spasmodic and shooting pain.
• Patient feels tremors.
• There occurs paralysis of lower limbs.
• There is trembling in the limbs with paralytic feeling.
• Well indicated medicine for chronic myelitis.
• The patient complains of lancinating pains like the electric shock.
• Numbness in fingers and toes, which extends to the lower limb, even involving the lower abdomen and perineum.
• There is paralysis in the lower limb.
• Formications begin in the fingers and extend through the pelvis, perineum and inner thighs to feet.
• There is twitching, trembling, spasms, weakness, heaviness, and uneasiness.
• There are cramps in the calves of legs.
• Well indicated for sciatica.
• Plays very important part in treating peripheral neuritis.
• There is paralysis of the lower limbs with atrophy.
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