Felty Syndrome is characterized as a complication of rheumatoid arthritis.
It is most common associated with more than 10 years of preceding RA activity.
FS patients are more likely to have a family history of RA
FS is characterized by the triad of Rheumatoid arthritis, spleenomegaly( enlargement of spleen) and abnormally low white blood count .
Although many patients with FS are asymptomatic, some develop serious and life-threatening infections secondary to granulocytopenia.
Felty syndrome is three times more common in females than in males.
Men are affected earlier in the course of RA than women. FS is most common in whites and is uncommon in blacks.
Cause is not known. A possibility is that the immune system is destroying white blood cells.
• Swelling in joints
• Loss of appetite
• Burning in eyes
• Pale skin
• Some patients with FS may have ulcers on the lower legs, and discoloration or abnormal brown pigmentation of the skin, particularly on the legs
• Presence of spleenomegaly , Hepatomegaly , Rheumatoid nodules.
• Mild elevations of alkaline phosphatase and transaminase levels may occur.
• Erythrocyte sedimentation rate (ESR) and serum immunoglobulin levels are invariably elevated in patients with FS.
• CBC( complete blood count )
• Portal hypertension
• Splenic rupture
• Gastrointestinal bleeding
• Sjogren syndrome
• Some medications prescribed, methotrexate, azathioprine, penicillamine, cyclosporin .
• Surgical removal of spleen in severe cases .
• Chronic arthritis with a feeling of bruising and soreness.
• Painful parts worse from being touched or moved.
• Swelling , inflammation of joints, rheumatism
• Swelling of ankles
• Heaviness and powerless, as if paralysed.
• Stinging, burning pains.
• Aggravation from heat, touch and on right side.
• Better by cold applications.
• Arthritis, gout with offensive, thick urine with sedimentation.
• Arthritic nodosities.
• Contraction especially fingers.
• Arthritic pains improve with heat and motion.
• Arthritis after chronic injury to joints.
• Joints become enlarge and hard, and nodes or deformities develop.
• Exostoses fingers, heels, arthritis nodositires.
• Nils hard and brittle, grown rapid.
• All complaints aggravated with cold
• Better by heat and continued motion
• Chronic Rheumatism
• Arthritis starts in lower joints and extends to the higher ones.
• Pain and inflammation often begins in the toes and spread upwards to ankles and knees.
• Swelling on joints significant and relieved by cold applications.
• The patient is worse from warmth
• Desires solitude.
• Rheumatic pains with stiffness, nodules and gout.
• Pain in small spots, often in small joints.
• Right shoulders, hip, knee and ankles.
• Whole body feels sore, as if beaten.
• Tenderness with swelling and occasional redness of the last joints of the fingers.
• Rheumatoid arthritis with pain and stiffness
• Hot baths or showers, and warmth improve stiffness and relieve pains.
• Extreme restless and unable to find a comfortable position.
• Worse in morning , first motion
• Better by continued movement
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