Vitamin B6/ Pyridoxine

Vitamin B6 is a water soluble vitamin i.e. it gets dissolved in water. The body cannot store them. The leftover amount of vitamin B6 leaves the body through urine. Vitamin B6 is the master vitamin for processing amino-acids, which are the building blocks of all proteins and some hormones. It also needed in making of hormones like serotonin, melatonin and dopamine. So a well-balanced diet with proper nutrients and well-balanced vitamin supplements is recommended.

IMPORTANCE

  • Pyridoxine is a vitamin. It can be found in certain foods such as cereals, beans, vegetables, liver, meat, and eggs. It can also be made in a laboratory.
  • Pyridoxine is used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and the “tired blood” (anaemia) that may result. It is also used for heart disease; high cholesterol; reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping clogged arteries stay open after a balloon procedure to unblock them (angioplasty).
  • Women use pyridoxine for premenstrual syndrome (PMS) and other menstruation problems, “morning sickness” (nausea and vomiting) in early pregnancy, stopping milk flow after childbirth, depression related to pregnancy or using birth control pills, and symptoms of menopause.
  • Pyridoxine is also used for Alzheimer’s disease, attention deficit-hyperactivity disorder (ADHD), Down syndrome, autism, diabetes and related nerve pain, sickle cell anemia, migraine headaches, asthma, carpal tunnel syndrome, night leg cramps,muscle cramps, arthritis, allergies, acne and various other skin conditions, and infertility. It is also used for dizziness, motion sickness, preventing the eye disease age-related macular degeneration (AMD), seizures, convulsions due to fever, and movement disorders (tardive dyskinesia, hyperkinesia, chorea), as well as for increasing appetite and helping people remember dreams.
  • Some people use pyridoxine for boosting the immune system, eye infections, bladder infections, and preventing cancer and kidney stones.
  • Pyridoxine is also used to overcome certain harmful side effects related to radiation treatment and treatment with medications such as mitomycin, procarbazine, cycloserine, fluorouracil, hydrazine, isoniazid, penicillamine, and vincristine.
  • Pyridoxine is frequently used in combination with other B vitamins in vitamin B complex products.

SOURCES

Meat

Vitamin B6 can be found in many common and versatile types of meats. Chicken, turkey, beef, and pork are all excellent sources of the nutrient. One serving of roasted chicken breast contains as much as 0.64mg of B6 and the same amount of turkey contains 0.54mg. Because meats are easy to incorporate into your diet through simple recipes and even snacks such as sandwiches, increasing your B6 intake by the consumption of meats is simple and effective.

Fish

As with meats, certain fish are rich in vitamin B6. Cod, salmon, halibut, trout, tuna and snapper are just some examples of fish which contain high levels of B6 and can form part of a healthy, balanced diet. Yellowfin tuna is one of the best dietary sources of vitamin B6 with 1.8mg found in a single serving. In addition to this, it is one of the healthiest sources of the nutrient. A serving of baked snapper or salmon contains 0.52mg and halibut contains 0.45mg.

Vegetables

Most vegetables typically contain reasonable levels of vitamin B6, but there are some vegetable powerhouses that are B6-rich. Bell peppers, spinach, baked potatoes (skin included), green peas, yams, broccoli, asparagus and turnip greens are all excellent sources of vitamin B6. These vegetables are also, for the most part, low in fat and contain other vitamins and nutrients that are essential for good health.

Nuts and Seeds

Peanuts, sunflower seeds, cashews and hazelnuts, which contain 0.6mg of 6 per serving – are all good sources of vitamin B6 and can be eaten as snacks or added to popular recipes.

Wholegrains and Bran

Whole-wheat bread, cereals, bran and other whole grains are rich in vitamin B6 and are probably already part of your daily diet. Wheat germ contains 3mg of vitamin B6 per 100g, making it one of the most valuable sources of the nutrient.

Beans and Legumes

Chickpeas, lentils and soybeans are just some examples of vitamin B6-rich beans and legumes. Kidney beans are another good source of the nutrient. By including a single serving of any of these foods with your meals, you can maintain your intake of vitamin B6 and lower the risk of experiencing B6 deficiency.

DIETERY REQUIREMENT

Paediatric referral range:
• Infants 0-6months                                 0.1 mg/day(adequate intake)
• Infants 7months-1 year                        0.3mg/day(adequate intake)
• Children 1-3 years                                   0.5 mg/day
• Children 4-8 years                                  0.6mg/day
• Children 9-13 years                                1 mg/day
• Boys 14-18 years                                    1.3 mg/day
• Girls 14-18 years                                     1.2 mg/day

Adult referral range:
• 19-50 years                                            1.3 mg/day
• Men 51 years and older                     1.7 mg/day
• Women 51 years and older              1.5 mg/day
• Pregnant women                                  1.9 mg/day
• Breast feeding women                        2.0 mg/day

INVESTIGATIONS OF VIT B6

Blood biochemistry.

INTERPRETATION OF VIT B6

The Higher amount of Vitamin B6 indicates:
• Difficulty coordinating movements
• Numbness
• Sensory changes
• Extreme sensitivity to sunlight
• Nausea
• Heartburn

LOWER AMOUNT OF VIT B6 INDICATES

• Confusion
• Convulsions
• Depression
• Insomnia
• Anemia
• Irritability
• Muscle twitching
• Dermatitis
• Mouth and tongue sores