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Acute Liver Failure

Acute liver failure(ALF) is a condition when liver loses its ability to perform its function rapidly.

acute liver failure

Acute liver failure refers to the rapid development of acute liver injury with impaired synthetic function and encephalopathy thus loses its ability to function normally. Commonly, Liver failure develops slowly over the course of time, but in case of acute liver failure, it develops in matter of days.

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    Acute liver failure is a medical emergency which requires hospitalization. In some cases it can be managed with proper medication; otherwise liver transplantation is the only alternative cure for AFL.
    Acute liver failure encompasses both:

    Fulminant hepatic failure:
    Fulminant hepatic failure is generally used to describe the development of encephalopathy within 8 weeks of the onset of symptoms in a patient with a previously healthy liver.

    Sub fulminant hepatic failure:
    Subfulminant hepatic failure is reserved for patients with liver disease up to 26 weeks before the development of hepatic encephalopathy.The development of cerebral edema is the major cause of mortality in patients with acute liver failure.

    Basics:
    An increase of intracranial blood volume and cerebral blood flow is a factor in acute liver failure.

    Age/Sex of Acute liver failure

    Viral hepatitis E and autoimmune liver disease are more common in women than in men

    What Causes Acute liver failure?

    Atypical causes of viral hepatitis and fulminant hepatic failure include the following:

    Cytomegalovirus

    Herpes simplex virus

    Epstein Barr virus

    Autoimmune diseases

    Drugs

    Portal vein thrombosis

    Hepatic vein thrombosis

    Hepatitis A

    Hepatitis B

    Hepatitis E

    Fructose intolerance

    Wilson disease.

    Some of the herbs are also associated with liver failure – Herbal supplements including kava, skullcap and pennyroyal.

    How Do I Get To Know About Acute liver failure ?

    Nausea and vomiting

    Pain in upper right area of abdomen

    Yellowing of skin and eyeballs

    Sleepiness

    Difficulty concentrating

    Disorientation or confusion

    Tests To Be Done For Acute liver failure

    • Patient history
    • Physical examination
    • Use of alcohol
    • Any medications
    • Family history

    Acute liver failure May Cause

    Acute renal failure

    Hemorrhage

    Seizures

    Infections

    Cerebral edema

    How Acute liver failure Is Compared

    • Eclampsia
    • Preeclampsia
    • Multiorgan failure
    • Alcoholic hepatitis

    How To Treat Acute liver failure

    • People with acute liver failure are treated in the intensive care unit of a hospital.
    • Medications for preventing bleeding
    • Screening for infections
    • Medications for fluid reduction in brain
    • Liver transplant
    • Because of the complexities involved, patients with ALF should be managed in an intensive care unit in centers with an active liver transplant program .

    Homeopathic treatment for Acute liver failure

    Antimonium crudum
    • Excess irritability, thick white tongue
    • Tendency to grow fat, cannot bear heat of sun
    • Sulky, with no wish to speak
    • Anger at every little attention

    Ignatia amara
    • Chief remedy for hysteria, adapted to nervous temperament.
    • Rapid change in mental and physical condition.
    • Effects of grief and sorrow, silent brooding
    • Lack of communication

    Chamomilla
    • Sensitive, irritable, thirsty hot and numb patients
    • Child wants many things but refuses when given
    • Impatient, sensitive to pain, always complaining
    • Complaints from anger
    • Mental calmness contraindicates

    Chelidonium majus
    • A prominent liver remedy, constant pain under inferior angle of right scapula.
    • Paralytic drawing and lameness in single parts
    • Hydrocele , great lethargy , distention in abdomen
    • Nausea, vomiting, better taking hot water

    Lycopodium
    • Liver functioning greatly disturbed.
    • Emaciation with debility in morning
    • Ascites in liver disease
    • Lack of vital heat

    Nux vomica
    • Flatulence distention, spasmodic colic
    • Liver engorged , weakness
    • Sour, bitter eructation , weight and pain in stomach.
    • Desire for fatty food

    Natrium sulphuricum
    • Liver remedy, feels every change from dry to wet
    • Symptoms worse in rainy weather
    • Vomiting sour , acid dyspepsia
    • Hepatitis ,flatulence with burning in abdomen

    Phosphorus
    • Yellow atrophy of liver and sub-acute hepatitis
    • Fatty degeneration’s of blood vessels
    • Pain in stomach relieved by cold food
    • Bad effects of salty food.

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