Psoriatic arthritis is a chronic disease characterized by a form of inflammation of the skin (psoriasis) and joints (inflammatory arthritis). Joint pain, stiffness, and swelling are the main symptoms of psoriatic arthritis that can lead to damage of the joint if left untreated.
Psoriatic arthritis is an autoimmune condition. An autoimmune condition occurs when the body’s immune system mistakenly sends inflammation to normal tissue/structures. In psoriatic arthritis, the inflammation is directed toward the joints causing inflammation swelling, redness, pain and stiffness, and damage.
Psoriatic arthritis can affect any joint of the body but usually affects the large joints, especially those of the lower extremities, distal joints of the fingers and toes, and also can affect the back and sacroiliac joints of the pelvis.
Asymmetric psoriatic arthritis: typically affects only a few joints. They can be large or small and anywhere in your body.
Distal interphalangeal predominant (DIP) psoriatic arthritis: mainly affects small joints at the ends of the fingers and toes, as well as the nails.
Spondylitis affects the backbone. It can cause inflammation and stiffness between your vertebrae
Arthritis mutilans: is the most severe and destructive form of psoriatic arthritis. Fortunately, it’s rare. It damages the small joints in your fingers and toes so badly that they become deformed.Causes of Psoriatic arthritis The cause is not exactly known. About 40 percent of patients with psoriatic arthritis have a family history of psoriasis or arthritis. Psoriatic arthritis can also result from an infection that activates the immune system. Signs and symptoms of Psoriatic arthritis • Painful, tender, stiff, hot, swollen and red joint.
•Elevations of the erythrocyte sedimentation rate (ESR) and C-reactive protein level.
•The Serum immunoglobulin A levels are increased
•Uric acid concentration may be increased.
Radiologic features have helped to distinguish psoriatic arthritis from other causes of arthritis.
Magnetic resonance imaging (MRI)
Arthrodesis and arthroplasty